Human Sera
Cayman Chemical TebIpenmhydrate 100mg
A STING agonist binds to wild-type and HAQ variant STING in a 3H-cGAMP filtration binding assay (EC50s 2.48 and 1.72 M respectively) induces secretion of IFN-B from THP-1 cells by 129 relative to induction by 23-cGAMP at 30 M reduces tumor growth in an MC-38 syngeneic mouse model of colon carcinoma in a dose-dependent manner and induces tumor regression at 450 g intratumorally and 50 mg/kg s.c. acts synergistically with an anti-PD-1 antibody in MC-38 CT26 B16/F10 and LL/2 syngeneic mouse models
Cayman Chemical FerroprotoporphyrIn 100mg
An internal standard for the quantification of quinapril by GC- or LC-MS
Cayman Chemical 2DeoxycytIdIn5OtrIphos 100mg
A ginsenoside with diverse biological activities enhances NK cytotoxicity against K562 cells in vitro at 10 UM and in vivo reduces atherosclerotic lesion area whole body MPO levels and aortic root NF-kB TLR4 and LOX-1 levels in ApoE-/- mice at 50 mg/kg increases microvessel density and improves focal cerebral blood perfusion in a rat model of MCAO-induced ischemic stroke restores spatial working memory in the APP/PS1 transgenic mouse model of Alzheimers disease
Cayman Chemical 5-EthynylurIdIn 100mg
A synthetic diterpene increases cytosolic GST activity and acid-soluble sulfhydryl levels in mouse liver and small bowel mucosa at 10 Umol once per day for three days
Cayman Chemical DeslorelInacetate 50mg
A synthetic non-steroidal estrogen prevents DMBA-induced mammary tumor formation in rats at 5 mg/animal s.c. prevents bone loss and uterine atrophy in ovariectomized rats
Cayman Chemical CJC-1295acetate 100mg
A gastric proton pump inhibitor (IC50 6 UM for isolated rabbit mucosa) reduces pentagastrin- or histamine-induced gastric acid secretion in anesthetized rats (ED50s 0.38 and 1.2 mg/kg respectively) reduces histamine-induced gastric acid secretion in Heidenhain pouch dogs
Cayman Chemical N-AcetylserotonIn 50mg
An analytical reference standard categorized as a synthetic cannabinoid metabolite a metabolite of ADB-BUTINACA intended for research and forensic applications
Cayman Chemical PseudomonIc ACDlIthIM sal 50mg
An analytical reference standard categorized as a synthetic cannabinoid metabolite a metabolite of 4-fluoro MDMB-BUTINACA intended for research and forensic applications
Cayman Chemical DM4hydrate 50mg
A GABA derivative increases parietal cortical blood flow in rats and rabbits at 50 mg/kg i.p. and 10 mg/kg i.v. respectively increases latency to enter the dark compartment in the passive avoidance conditioned reflex test in rats at 10 mg/kg compared with control animals
Cayman Chemical CLOrmethIazolehydroCLOrId 50mg
A GABA receptor modulator binds to GABAA and GABAB receptors (IC50s 1 and 0.35 UM respectively) inhibits GABA uptake in rat brain synaptosomes (IC50 67 UM) induces currents in a patch-clamp assay using Xenopus oocytes expressing human GABAC (EC50 19 UM) inhibits electrical discharges in the amygdala in a cat model of N-amidinobenzamide-induced seizures at 20 mg/animal
Cayman Chemical Cordyceps mIlItarIs 100mg
The dextrorotary isomer of L-DOPA converted to L-DOPA via sequential oxidation and transamination which are mediated by DAAO and DOPA transaminase respectively in rat kidney homogenates reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner increases striatal dopamine levels in rats at 200 Ug/animal induces contralateral turns in a rat model of 6-OHDA-induced Parkinsons disease at 20 mg/kg
Cayman Chemical DIgItls pururea DIgItIn 100mg
A synthetic CB which has a higher affinity for the peripheral CB2 receptor (Ki 0.64 nM) over the central CB1 receptor (Ki 270 nM) displays analgesic anti-inflammatory and anti-hyperalgesic effects in mice
Cayman Chemical Zaltoprofen 50mg
Antigen a peptide within the region of amino acids 1-50 of human RORY Host rabbit Cross Reactivity ( ) chimpanzee and human RORY predicted to react with bovine canine mouse and rat RORY Application(s) IHC and WB
Cayman Chemical OxprenololhydrochlorIde 100mg
15(R)-PGE1 is the “unnatural” C-15 stereoisomer of PGE1. It is essentially inactive biologically when compared to PGE1.{1350} It is a non-competitive inhibitor of 15-hydroxy PGDH with an IC50 of 189 UM.{2274}
Cayman Chemical PIcrocrocIn 100mg
A peptide inhibits flow-based adhesion of primary human neutrophils to HUVECs